Table 3.

Indications for treatment with renin-angiotensin aldosterone system inhibitors

	When indicated	When to consider	Target	Comment
Blood pressure (office or ABPM)	Repeated blood pressure >90th percentile for height and gender		<50th percentile for height and gender (if tolerated); <75th percentile otherwise	Perform ABPM when office blood pressure is elevated to rule out white coat hypertension
Urine albumin creatinine ratio	>300 mg/g in first morning or 24-h urine sample	30–299 mg/g in first morning or 24-h urine sample	<30 mg/g in first morning or 24-h urine sample
Estimated glomerular filtration rate	No data available	No data available	>90 ml/min/1.73 m2	Consult pediatric nephrologist when eGFR decreases >5 ml/min/1.73 m2 over 2 yr, or to <90 ml/min/1.73 m2

ABPM = ambulatory blood pressure monitoring; eGFR = estimated glomerular filtration rate.