Table 2.
Gleason score, and PTEN and ERG status stratified by SRPK1 in the TURP cohort (n = 480)a
| Variables | SRPK1 (0, 1, 2) | SRPK1 (3) | p value |
|---|---|---|---|
| Gleason score | |||
| ≤6 | 134 (38) | 15 (14) | <0.0001 |
| 3 + 4 | 25 (7) | 7 (7) | |
| 4 + 3 | 43 (12) | 7 (7) | |
| 8 | 23 (7) | 5 (5) | |
| 9–10 | 126 (36) | 74 (69) | |
| PTEN intensity | |||
| Negative | 105 (29) | 51 (46) | 0.001 |
| Positive | 260 (71) | 61(55) | |
| ERG dual | |||
| Negative | 271 (74) | 76 (68) | 0.184 |
| Positive | 94 (26) | 36 (112) | |
SRPK1 = serine-arginine protein kinase 1; TURP = transurethral resection of the prostate.
a
SRPK1 scores: 0, negative; 1, weak; 2, moderate; and 3, high.