Table 5.

Comparison, by risk level, of men's EORTC QLQ-C30 mean scores at baseline and follow-up

Scales	Risk level	Baseline		Follow-up			Between-group difference at follow-up a
		N	Mean (SD)	N	Mean (SD)	p value b	Adj. Mean diff. (99% CI)	p value
Global health status c
	Low risk	421	81 (19)	421	82 (19)	0.4	–
	Intermediate risk	421	84 (16)	421	85 (14)	0.03	1.5 (–0.7 to 3.7)	0.1
	High risk	93	82 (17)	93	85 (14)	0.03	2.4 (–1.2 to 6.0)	0.1
	PCa diagnosis	59	82 (15)	59	84 (13)	0.2	1.4 (–3.0 to 5.7)	0.4
Physical functioning c
	Low risk	420	96 (11)	420	96 (10)	0.4	–
	Intermediate risk	421	97 (9)	421	97 (8)	0.4	–0.1 (–1.1 to 0.9)	0.8
	High risk	93	98 (7)	93	98 (7)	0.4	0.5 (–1.1 to 2.1)	0.4
	PCa diagnosis	59	98 (6)	59	99 (4)	0.05	1.6 (–0.4 to 3.6)	0.04
Role functioning c
	Low risk	421	94 (17)	419	94 (18)	0.6	–
	Intermediate risk	421	96 (14)	420	96 (12)	0.9	1.3 (–0.9 to 3.5)	0.1
	High risk	93	94 (14)	93	95 (12)	0.4	1.5 (–2.1 to 5.2)	0.3
	PCa diagnosis	59	92 (19)	59	97 (11)	0.02	4.0 (–0.5 to 8.4)	0.03
Emotional functioning c
	Low risk	421	88 (16)	419	89 (16)	0.4	–
	Intermediate risk	420	89 (16)	421	91 (14)	0.006	1.4 (–0.7 to 3.6)	0.08
	High risk	93	90 (15)	93	91 (16)	0.7	1.2 (–2.3 to 4.8)	0.4
	PCa diagnosis	59	91 (13)	59	88 (14)	0.09	1.2 (–2.3 to 4.8)	0.1
Cognitive functioning c
	Low risk	421	91 (14)	420	90 (15)	0.3	–
	Intermediate risk	420	92 (14)	421	92 (13)	0.6	1.1 (–0.8 to 3.1)	0.1
	High risk	93	90 (15)	93	90 (14)	0.9	–0.1 (–3.4 to 3.2)	0.9
	PCa diagnosis	59	92 (14)	59	89 (14)	0.1	–0.1 (–3.4 to 3.2)	0.3
Social functioning c
	Low risk	420	94 (16)	417	95 (14)	0.2	–
	Intermediate risk	420	94 (15)	420	95 (14)	0.2	0.4 (–1.7 to 2.6)	0.6
	High risk	93	92 (17)	93	94 (14)	0.2	0.0 (–3.6 to 3.6)	0.9
	PCa diagnosis	59	95 (11)		94 (13)	0.5	–1.3 (–5.7 to 3.1)	0.4
Pain d
	Low risk	421	11 (20)	420	11 (19)	0.6	–
	Intermediate risk	420	10 (18)	421	9 (18)	0.7	–0.6 (–3.2 to 2.0)	0.5
	High risk	93	10 (18)	93	8 (14)	0.2	–2.1 (–6.4 to 2.3)	0.2
	PCa diagnosis	59	12 (21)	59	6 (12)	0.04	–5.4 (–10.7 to –0.12)	0.009
Fatigue d
	Low risk	421	15 (18)	420	14 (19)	0.8	–
	Intermediate risk	420	13 (17)	421	12 (15)	0.09	–1.4 (–3.7 to 0.8)	0.1
	High risk	93	13 (16)	93	12 (15)	0.3	–1.9 (–5.7 to 1.9)	0.2
	PCa diagnosis	59	14 (15)	59	10 (13)	0.02	–4.0 (–8.6 to 0.6)	0.02

Adj. Mean diff. = adjusted mean difference; ANCOVA = analysis of covariance; CI = confidence interval; PCa = prostate cancer; SD = standard deviation.

^aAdjusted mean difference at follow-up of pairwise comparisons with low-risk group by using ANCOVA, adjusted for baseline.

^bPaired Wilcoxon signed rank test.

^cRange 0–100; high levels represent high levels of functioning and quality of life.

^dRange 0–100; high levels represent high levels of problems.