Table 2.
Hazard ratio for recurrence of prostate cancer according to the degree of nerve-sparing in radical prostatectomy
| Hazard ratio (95% confidence interval) |
|||
|---|---|---|---|
| Unadjusted | Adjusted A a | Adjusted B b | |
| Degree of nerve-sparing | |||
| None | 1.00 | 1.00 | 1.00 |
| Semi | 0.61 (0.42–0.89) | 0.85 (0.62–1.17) | 0.85 (0.63–1.15) |
| Interfascial | 0.58 (0.45–0.74) | 1.11 (0.88–1.39) | 1.08 (0.89–1.30) |
| Intrafascial | 0.56 (0.39–0.81) | 1.02 (0.67–1.57) | 1.03 (0.69–1.53) |
| Preoperative PSA | – | 1.06 (1.02–1.10) | 1.06 (1.02–1.10) |
| Age at surgery | – | 1.02 (1.00–1.03) | 1.02 (1.00–1.03) |
| ISUP grade in surgical specimen | |||
| Grade 1 | – | 1.00 | 1.00 |
| Grade 2 | – | 2.19 (1.68–2.86) | 2.20 (1.69–2.87) |
| Grade ≥3 | – | 4.33 (2.93–6.41) | 4.35 (2.94–6.44) |
| Pathological tumour stage | |||
| pT2 | – | 1.00 | 1.00 |
| pT3/4 | – | 1.93 (1.59–2.34) | 1.92 (1.59–2.32) |
| Prostate weight | – | 0.99 (0.98–1.00) | 0.99 (0.98–1.00) |
| Prior procedures performed by OpS | |||
| <100 | – | – | 1.00 |
| ≥100 | – | – | 1.04 (0.75–1.43) |
| Annual procedures performed by OpS | |||
| <50 | – | – | 1.00 |
| ≥50 | – | – | 1.09 (0.82–1.45) |
ISUP = International Society of Urological Pathology; OpS = operating surgeon.
a
Adjusted for age at surgery, preoperative prostate-specific antigen, ISUP grade in surgical specimen, pathological tumour stage, and prostate weight.
b
Adjusted for age at surgery, preoperative prostate-specific antigen, ISUP grade in surgical specimen, pathological tumour stage, prostate weight, surgeon prior experience, and surgeon annual volume.