Fig. 2.

Example of a patient case. (A,B) Screening T2-weighted and diffusion-weighted MRI revealed a distinct focus graded as a Likert 5 lesion, which was also present on (C) ¹⁸F-PSMA-1007 PET-CT (maximum standardized uptake value 44.6) (c). The patient underwent (D) targeted hemiablation, during which the targeted prostate region reached a lethal minimum temperature of 55 °C. (E) The nonperfused volume can be visualized immediately after treatment, which demonstrates the acute ablation effect. At 12 mo the patient underwent additional follow-up imaging. (F,H) Multiparametric MRI and (G) ¹⁸F-PSMA-1007 PET-CT were both negative. The prostate volume decreased from 18 to 10 cm³ (56%) at 12 mo. The imaging findings agree with a post-sTULSA biopsy, which showed no vital cancer. MRI = magnetic resonance imaging; PSMA-1007 = prostate-specific membrane antigen ligand 1007; PET = positron emission tomography; CT = computed tomography; sTULSA = salvage MRI-guided transurethral ultrasound ablation.