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. 2021 Jul 14;11:698150. doi: 10.3389/fonc.2021.698150

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Copyright © 2021 Boekhoff, Bison, Genzel, Eveslage, Otte, Friedrich, Flitsch and Müller

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Self-assessment (A, C, E) and parental assessment (B, D, F) of quality of life by Pediatric Quality of Life questionnaire (PEDQOL) in childhood-onset craniopharyngioma (CP) patients, recruited in KRANIOPHARYNGEOM 2007 between 2007 and 2019, with regard to cerebral infarction (CI) confirmed by central neuroradiological review. White boxes: CI, and black boxes: no CI. PEDQOL scores are shown as negative rating at the time points three months (A, B), one year (C, D), and three years (E, F) after CP diagnosis. The horizontal line in the middle of the box depicts the median. The top and bottom edges of the box respectively mark the 25^th and 75^th percentiles. Whiskers indicate the range of values that fall within 1.5 box-lengths.