Figure 5.
Bar plots showing percent differences in methylation generated from logistic regression across CpG sites in the gene body of esr1. (A) indicates percent methylation differences in liver at Day 2 across treatment groups and females compared to control. (B) indicates percent methylation differences across treatment groups and females compared to control at Day 2 in brain. All significant CpG sites are denoted by asterisks (FDR < 0.10). Low EE2 dose is measured at 1.4 ± 0.31 ng/L and high EE2 dose is 3.5 ± 1.34 ng/L.
