TABLE 2.
Eight disease/functional annotations according to the IPA database.
| Diseases or functions annotation | p-value | Predicted activation state | Activation z-score | Molecules |
| Size of body | 1.17E-02 | Decreased | −2.545 | APBA2,BMP4,CD9,CPLX1,CSGALNACT1,DBH,HDAC4,HOXD4,LHCGR,LTBP3, PARK2,POSTN,REN,SLC6A3,STARD13,WWOX |
| Development of body trunk | 1.98E-03 | Decreased | −2.531 | ARID3B,ATF7,BCL11B,BMP4,CD9,FOXP1,HDAC4,HOXA3,IL1B,JARID2,LHCGR, MAD1L1,NCOR2,NRG4,PTPRN2,REN,RLTPR,RPTOR,SCHIP1,STARD13,VCAN |
| Activation of lymphocytes | 1.24E-02 | Decreased | −2.400 | BCL11B,BHLHE40,GADD45A,HDAC4,IL1B,IL21R,NCOR2,NFKBIZ,REN,TPO |
| Activation of mononuclear leukocytes | 6.48E-03 | Decreased | −2.391 | BCL11B,BHLHE40,FOXP1,GADD45A,HDAC4,IL1B,IL21R,NCOR2,NFKBIZ,REN,TPO |
| Synthesis of lipid | 4.57E-03 | Decreased | −2.335 | BMP4,C1QTNF3,CCHCR1,CD9,CERS6,CNTFR,CUX1,DEGS2,IL1B,LHCGR,LPIN1,REN,RPTOR,TBXAS1,WWOX |
| Synthesis of steroid | 2.14E-03 | Decreased | −2.115 | BMP4,C1QTNF3,CCHCR1,IL1B,LHCGR,REN,TBXAS1,WWOX |
| Secretion of lipid | 4.43E-03 | Decreased | −2.052 | BCL11B,BHLHE40,BMP4,IL1B,LHCGR,PTPRN2 |
| Secretion of molecule | 2.25E-03 | Decreased | −2.024 | BCL11B,BHLHE40,BMP4,C1QTNF3,CASP4,CPLX1,DBH,IL1B,LHCGR,PARK2, PTPRN2,SGK1,SLC6A3 |
Bold indicates validated genes.