Table 3.
Logistic regression analysis for the identification of predictors for positive surgical margins after surgery in nerve-sparing procedures
| Variable | Univariable | Multivariable | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p-value | OR | 95% CI | p-value | |
| Risk class low intermediate high |
1.0 1.15 0.48 |
– 0.53–2.52 0.01–20.97 |
– 0.72 0.70 |
1.0 2.44 14.63 |
– 0.75–7.91 0.01–189.13 |
– 0.14 0.84 |
| mpMRI PI–RADS 1–2 3 4–5 |
1.0 0.38 0.45 |
– 0.20–7.40 0.03–7.55 |
– 0.53 0.58 |
1.0 2.21 2.45 |
– 0.02–256.85 0.02–265.24 |
– 0.74 0.71 |
| Surgical procedure LRP RARP |
1.0 1.95 |
– 0.93–4.12 |
– 0.08 |
1.0 1.86 |
– 0.69–5.03 |
– 0.22 |
| NS procedure monolateral bilateral |
1.0 1.27 |
– 0.61–2.66 |
– 0.52 |
1.0 2.14 |
– 0.74–6.19 |
– 0.16 |
| Pathologic T stage pT2 pT3a pT3b |
1.0 2.09 1.44 |
– 0.94–4.63 0.12–16.57 |
– 0.07 0.77 |
1.0 2.60 1.75 |
– 0.86–7.81 0.12–24.59 |
– 0.09 0.68 |
| ISUP at surgery 1 2 3 4 5 |
1.0 1.20 0.94 0.83 7.44 |
– 0.52–2.80 0.28–3.19 0.01–80.49 0.08–724.61 |
– 0.67 0.92 0.93 0.39 |
1.0 1.11 1.03 1.63 17.41 |
– 0.32–3.86 0.20–5.36 0.01–191.91 0.02–14615.21 |
– 0.87 0.97 0.84 0.41 |
| PNI at surgery absent present |
1.0 0.89 |
– 0.42–1.88 |
– 0.76 |
1.0 1.04 |
– 0.37–2.94 |
– 0.94 |
OR – odds ratio; CI – confidence interval; mpMRI – multiparametric magnetic resonance imaging; PI-RADS – Prostate Imaging -Reporting and Data System; LRP – laparoscopic radical prostatectomy; RARP – robot-assisted radical prostatectomy; NS – nerve-sparing; ISUP – International Society of Urological Pathology; PNI – perineural invasion