Table 1.

Reaction Development^a

Entry	THIQ (equiv)	Solvent	T (°C)	Time (min)	Yield (%)	dr
1	1.3	PhMe	reflux	60	56	1:1
2	1.3	DCE	reflux	60	58	1.3:1
3b	1.3	PhMe	150	5	61	1.1:1
4b	1.3	DCE	150	5	76	1:1
5b	2.0	DCE	150	5	61	1.1:1
6b	1.3	DCE	100	5	71	1.4:1
7b	1.3	DCE	100	15	75	1.2:1

^aReactions were performed on a 0.25 mmol scale. All yields correspond to isolated yields. The dr was determined by ¹H NMR analysis after purification.

^bPerformed under microwave irradiation.