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. 2021 Jul 16;17(7):e1009761. doi: 10.1371/journal.ppat.1009761

Fig 4. M protein-specific cTfh responses increase from the first to the second convalescent visit (N = 26).

Fig 4

(A) Paired convalescence Visit 1 and Visit 2 CD4 T-cell and cTfh response magnitudes by AIM (p values determined by Fisher’s Exact Test). (B) Paired CD4 T-cell and cTfh response magnitudes for AIM (p values determined by a paired Wilcoxon Signed-Rank Test). (C) Flow plots for both the first (top) and second (bottom) convalescent visit of individuals where robust cTfh responses (>5%) developed. Unstimulated negative control shown for each. SARS-CoV-2 protein to which response is directed is listed next to the PTID in parentheses. Positive SARS-CoV-2-specific responses are indicated by gate frequencies in red.