Table 4. Multivariable analysis for the probability of hospitalization.
Variables | OR | 95% CI | P-value |
---|---|---|---|
Age (for each year) | 1.033 | 1.023–1.044 | <0.001 |
Hypertension (yes vs. no) | 1.418 | 1.076–1.869 | 0.013 |
Cardiovascular disease (yes vs. no) | 1.648 | 1.077–2.523 | 0.021 |
Recent high dose of steroids (yes vs. no) | 1.866 | 1.229–2.832 | 0.003 |
Time of symptoms (for each day) | 0.983 | 0.971–0.996 | 0.008 |
Fever (yes vs. no) | 1.649 | 1.290–2.108 | <0.001 |
Dyspnea (yes vs. no) | 3.673 | 2.803–4.812 | <0.001 |
Nasal congestion (yes vs. no) | 0.588 | 0.410–0.845 | 0.004 |
Headache (yes vs. no) | 0.525 | 0.402–0.685 | <0.001 |
Arthralgia (yes vs. no) | 0.250 | 0.117–0.533 | <0.001 |
Diarrhea (yes vs. no) | 1.783 | 1.367–2.325 | <0.001 |
Anosmia (yes vs. no) | 0.519 | 0.387–0.696 | <0.001 |
Nausea and vomiting (yes vs. no) | 2.284 | 1.427–3.655 | 0.001 |
AKI, acute kidney injury; eGFR, estimated glomerular filtration rate.
Footnote: Variables included in the modeling: age, type of donor (living vs. deceased); hypertension, diabetes, previous cardiovascular disease, and neoplasia as comorbidities; recent use of high dose of steroids and recent use of Thymoglobulin; time of the start of COVID-19 symptoms; fever, chills, cough, dyspnea, runny nose, headache, nasal congestion, sore throat, myalgia, arthralgia, diarrhea, nausea and vomiting, anosmia, and ageusia as COVID-19 symptoms.
Values with missing values < 10%: recent use of high dose of steroids and recent use of Thymoglobulin. For both the mode value was imputed, i.e., no use.
Variables excluded from the modeling:
a) number of missing were higher than 10%: eGFR (10.9%) and AKI (37.4%)
b) collinearity: hypoxemia (colinear with dyspnea).