Table 1. Clinical and imaging characteristics for retrospective CS cohort.
Missing | Overall | No clinical VT | Clinical VT | P | |
n | 45 | 29 | 16 | ||
Demographic and clinical characteristics | |||||
Age (years) | 0 | 54 (11) | 54 (9) | 53 (14) | 0.674 |
Female sex | 0 | 20 (44%) | 16 (55%) | 4 (25%) | 0.102 |
Weight (kg) | 1 | 91.8 (22.2) | 89.2 (20.9) | 96.6 (24.4) | 0.327 |
Enhancement present on LGE-MRI |
0 | 32 (71%) | 18 (62%) | 14 (88%) | 0.094 |
Abnormal uptake on FDG-PET |
0 | 32 (71%) | 18 (62%) | 14 (88%) | 0.094 |
LVEF | 0 | 50.6 (14.7) | 52.0 (15.4) | 48.1 (13.5) | 0.376 |
QRS duration (ms) | 3 | 114 (31) | 107 (29) | 126 (33) | 0.079 |
Follow-up and clinical events | |||||
Time between MRI and PET (days) |
4* | 53 [28, 158] | 55 [29, 161] | 53 [18, 138] | 0.808 |
Follow-up duration (days) | 0 | 624 [244, 925] | 600 [322, 847] | 677 [100, 1071] | 0.713 |
ICD implantation | 0 | 16 (36%) | 5 (17%) | 11 (69%) | 0.002 |
Appropriate shock | 0 | 5 (11%) | 0 (0%) | 5 (31%) | 0.004 |
Burden of disease remodeling (as % of myocardial volume) | |||||
Nondiseased | 0 | 0.652 (0.251) | 0.718 (0.235) | 0.532 (0.241) | 0.018 |
Fibrosis | 0 | 0.153 (0.034) | 0.144 (0.029) | 0.170 (0.035) | 0.019 |
Inflammation | 0 | 0.236 (0.297) | 0.163 (0.275) | 0.368 (0.298) | 0.031 |
Fibrosis-inflammation overlap |
0 | 0.041 (0.054) | 0.025 (0.044) | 0.070 (0.058) | 0.013 |
Fibrosis, excluding overlap with inflammation |
0 | 0.112 (0.056) | 0.119 (0.049) | 0.100 (0.066) | 0.328 |
Inflammation, excluding overlap with fibrosis |
0 | 0.195 (0.248) | 0.138 (0.233) | 0.298 (0.248) | 0.043 |
*Exact dates for both MRI and PET are unavailable for four patients because of heterogeneous deidentification procedures, but patients were only included in the study if it could be determined that their MRI and PET were acquired less than 1 year apart. No patients in the cohort experienced inappropriate shocks during follow-up.