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. 2021 Jul 28;7(31):eabi8020. doi: 10.1126/sciadv.abi8020

Table 1. Clinical and imaging characteristics for retrospective CS cohort.

Values are provided as means (SD), n (%), or median [Q1, Q3] as appropriate. P values were calculated with two-sided two-sample t test, chi-square test, Fisher’s exact test, or Kruskal-Wallis test.

Missing Overall No clinical VT Clinical VT P
n 45 29 16
Demographic and clinical characteristics
  Age (years) 0 54 (11) 54 (9) 53 (14) 0.674
  Female sex 0 20 (44%) 16 (55%) 4 (25%) 0.102
  Weight (kg) 1 91.8 (22.2) 89.2 (20.9) 96.6 (24.4) 0.327
  Enhancement present on
LGE-MRI
0 32 (71%) 18 (62%) 14 (88%) 0.094
  Abnormal uptake on
FDG-PET
0 32 (71%) 18 (62%) 14 (88%) 0.094
  LVEF 0 50.6 (14.7) 52.0 (15.4) 48.1 (13.5) 0.376
  QRS duration (ms) 3 114 (31) 107 (29) 126 (33) 0.079
Follow-up and clinical events
  Time between MRI and
PET (days)
4* 53 [28, 158] 55 [29, 161] 53 [18, 138] 0.808
  Follow-up duration (days) 0 624 [244, 925] 600 [322, 847] 677 [100, 1071] 0.713
  ICD implantation 0 16 (36%) 5 (17%) 11 (69%) 0.002
  Appropriate shock 0 5 (11%) 0 (0%) 5 (31%) 0.004
Burden of disease remodeling (as % of myocardial volume)
  Nondiseased 0 0.652 (0.251) 0.718 (0.235) 0.532 (0.241) 0.018
  Fibrosis 0 0.153 (0.034) 0.144 (0.029) 0.170 (0.035) 0.019
  Inflammation 0 0.236 (0.297) 0.163 (0.275) 0.368 (0.298) 0.031
  Fibrosis-inflammation
overlap
0 0.041 (0.054) 0.025 (0.044) 0.070 (0.058) 0.013
  Fibrosis, excluding overlap
with inflammation
0 0.112 (0.056) 0.119 (0.049) 0.100 (0.066) 0.328
  Inflammation, excluding
overlap with fibrosis
0 0.195 (0.248) 0.138 (0.233) 0.298 (0.248) 0.043

*Exact dates for both MRI and PET are unavailable for four patients because of heterogeneous deidentification procedures, but patients were only included in the study if it could be determined that their MRI and PET were acquired less than 1 year apart. No patients in the cohort experienced inappropriate shocks during follow-up.