Table 2.
HFpEF (N = 55) | Control (N = 33) | Unadjusted data | Adjusted data a | ||||
---|---|---|---|---|---|---|---|
Median | IQR | Median | IQR | P | β (SE) | P | |
RV EAT, mm | 4.6 | 3.5–5.5 | 3.2 | 2.5–3.9 | <0.001 | 0.2 (0.1) | 0.03 |
AV groove EAT, mm | 19.2 | 14.9–24.5 | 14.9 | 13.6–17.4 | 0.001 | 2.8 (1.6) | 0.08 |
Liver FF, % | 6.4 | 4.2–10.3 | 4.1 | 0.9–6.4 | 0.001 | 0.5 (0.2) | 0.04 |
Abdominal VAT, cm2 | 201.2 | 108.2–242.8 | 76.8 | 52.6–142.2 | <0.001 | 22.1 (20.0) | 0.27 |
Abdominal SAT, cm2 | 388.0 | 267.1–517.1 | 247 | 154.3–328.8 | 0.001 | 52.6 (30.9) | 0.09 |
Abdominal VAT/SAT ratio | 0.48 | 0.37–0.69 | 0.36 | 0.3–0.5 | 0.03 | 0.02 (0.15) | 0.87 |
Thigh SAT, cm2 | 182.3 | 105.2–258.9 | 123.5 | 75.4–163 | 0.002 | 0.12 (0.12) | 0.34 |
Thigh IMAT, cm2 | 27.0 | 16–42 | 15.8 | 15.1–21.6 | 0.06 | 0.29 (0.19) | 0.12 |
Thigh IMAT FF, % | 22.3 | 16.2–28.9 | 14.3 | 11.8–17.4 | 0.006 | 0.33 (0.18) | 0.06 |
Thigh interMF, cm2 | 11.0 | 7.2–18.1 | 5.0 | 4.1–6.8 | <0.001 | 0.60 (0.20) | 0.003 |
Thigh intraMF, cm2 | 16.5 | 10.8–24.8 | 11.7 | 10.8–16 | 0.11 | 0.17 (0.13) | 0.18 |
Thigh muscle, cm2 | 124.4 | 102.4–157.5 | 122.5 | 93.6–143.6 | 0.71 | −2.98 (15.32) | 0.85 |
Psoas muscle, cm2 | 16.4 | 13.7–20.6 | 12.3 | 8.3–19.9 | 0.06 | 0.17 (0.10) | 0.10 |
Paraspinal muscle, cm2 | 34.7 | 29.8–43.4 | 21.1 | 18.1–31.7 | <0.001 | 7.57 (3.01) | 0.01 |
AV, atrioventricular; EAT, epicardial adipose tissue; FF, fat fraction; HFpEF, heart failure with preserved ejection fraction; IMAT, intermuscular adipose tissue; interMF, intermuscular fat; intraMF, intramuscular fat; IQR, interquartile range; IQR, interquartile range; RV, right ventricular; SAT, subcutaneous adipose tissue; SE, standard error; VAT, visceral adipose tissue.
Analyses are adjusted for age, sex, and body surface area. Positive β coefficients indicate higher values in HFpEF patients than controls.