Figure 1.

Study flow chart. Overview of screened, eligible, included, and excluded patients. Assessments included a physical examination, echocardiography, laboratory testing, the Minnesota Living with Heart Failure Questionnaire, the EQ‐5D‐3L questionnaire, the Epworth Sleepiness Scale, and the New York Heart Association score. Polygraphy was performed for Groups 1–3 at baseline and at 3 months for Groups 1 and 2. AHI, apnoea–hypopnoea index; CPAP, continuous positive airway pressure; HF, heart failure; PV, protocol violation; SV, sacubritil–valsartan.