Table 3.
Group data for CrCEST asymmetry, an index of free creatine (Cr), in the lateral gastrocnemius following a standardized plantar flexion exercise protocol
| Healthy | Hypertensive | HFpEF | P‐value | |
|---|---|---|---|---|
| (n = 20) | (n = 17) | (n = 14) | ||
| Baseline CrCEST asymmetry, % | 6.2 ± 0.9 | 6.0 ± 1.2 | 6.3 ± 1.4 | 0.73 |
| Increase in CrCEST asymmetry post‐exercise, % | 8.3 ± 3.5 | 7.8 ± 2.9 | 6.2 ± 2.3 | 0.16 |
| Half‐time CrCEST recovery, s | 127.6 (101.1, 147.5) | 114.4 (87.9, 154.1) | 167.4 a , b (140.9, 458.9) | 0.005 |
| Slope of early Cr recovery, %Asymmetry/s | −0.06 ± 0.03 | −0.05 ± 0.02 | −0.03 ± 0.02 a | 0.01 |
Data are presented as mean ± SD or median (25–75% interquartile range).
IQR, interquartile range; SD, standard deviation.
a
HFpEF vs. healthy, adjusted P < 0.05.
b
HFpEF vs. HTN, adjusted P < 0.05.
c
Healthy vs HTN, adjusted P < 0.05.