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. 2021 May 2;8(4):2741–2754. doi: 10.1002/ehf2.13344

Table 2.

Univariable associations of baseline characteristics and left ventricular ejection fraction

Clinical characteristics Mean difference (95% CI)* P value* r a R 2 * Pseudo R 2 lower bound b Pseudo R 2 upper bound b
Age, years 0.31 (0.25–0.37) <0.001 0.222 0.063 0.067 0.055
Female 6.89 (5.51–8.28) <0.001 0.229 0.005 0.050 0.046
Weight, kg c −0.01 (−0.16 to 0.17) 0.923 −0.017 <0.001 <0.001 <0.001
Systolic blood pressure, mmHg c 1.23 (0.96–1.49) <0.001 0.214 0.046 0.042 0.038
Comorbidities
Atrial fibrillation 2.37 (0.94–3.80) 0.001 0.072 0.006 0.007 0.004
Cerebrovascular disease 1.89 (−0.46 to 4.23) 0.115 0.038 0.002 0.002 0.002
COPD 3.09 (1.45–4.74) <0.001 0.088 0.008 0.007 0.007
Diabetes 1.05 (−0.37 to 2.47) 0.148 0.038 0.001 0.001 0.002
PCI/CABG −2.63 (−4.17 to −1.08) 0.001 −0.089 0.007 0.005 0.005
Severe valvular heart disease 0.41 (−1.39 to 2.22) 0.655 0.008 <0.001 <0.001 <0.001
Sleep apnoea 0.60 (−1.61 to 2.82) 0.592 0.017 <0.001 0.001 <0.001
Laboratory analysis
Creatinine, μmol/L c −0.02 (−0.09 to 0.06) 0.680 −0.004 <0.001 <0.001 <0.001
Sodium, mmol/L −0.03 (−0.18 to 0.11) 0.652 0.014 <0.001 <0.001 <0.001
Troponin I, ng/L 0.38 (−0.75 to −0.01) 0.050 −0.257 0.004 0.005 0.005
NT‐proBNP, ng/L d −0.04 (−0.05 to −0.03) <0.001 −0.282 0.003 0.028 0.029

CI, confidence interval; COPD, chronic obstructive pulmonary disease; NT‐proBNP, N‐terminal pro brain natriuretic peptide.

*

Mean difference and confidence intervals, R 2 value, and P value derived from univariable linear regression analysis.

a

r value derived from correlation analysis.

b

Pseudo R 2 value derived from interval regression analysis (six left ventricular ejection fraction categories using per 10% cut‐offs).

c

Per a unit of 10.

d

Per a unit of 100.