Table 2.
Quality of life in patients with HFpEF, HFrEF and non‐HF controls
| Parameters of quality of life | Non‐HF controls | HFrEF | HFpEF | P‐value |
|---|---|---|---|---|
| N = 20 | N = 18 | N = 17 | ||
| Physical functioning (PF) | 58.2 [56.2–60.4] | 50.9 [46.1–54.2]** | 51.8 [43.7–55.3]* | <0.0001 |
| Role limitation because of physical problems (RP) | 56.8 [53.5–59.0] | 48.0 [41.0–55.8]** | 47.4 [42.4–51.6]* | 0.002 |
| Bodily pain (bp) | 61.7 [54.3–63.3] | 51.3 [39.6–62.1] | 49.5 [38.7–60.1]* | 0.01 |
| General health (GH) | 55.4 ± 9.8 | 46.1 ± 6.0** | 47.2 ± 8.6* | 0.006 |
| Vitality (VT) | 57.1 ± 5.2 | 53.6 ± 8.6 | 47.5 ± 8.4* , † | 0.004 |
| Social functioning (SF) | 57.6 [55.7–58.3] | 57.2 [43.8–57.8] | 46.7 [44.8–50.2]* | 0.002 |
| Role limitation because of emotional health (RE) | 55.5 [50.6–56.3] | 53.9 [41.4–56.2] | 48.9 [44.1–55.7] | 0.08 |
| Mental health (MH) | 52.5 ± 7.0 | 50.2 ± 11. 7 | 45.2 ± 8.5 | 0.09 |
| Physical score component (PCS) | 56.3 ± 3.8 | 45.6 ± 5.9** | 47.5 ± 8.3* | <0.0001 |
| Mental score component (mcs) | 50.5 ± 5.0 | 50.2 ± 10.0 | 43.6 ± 7.1* , † | 0.03 |
| EQ‐5D (VAS) | 85.0 [80–95.0] | 65.0 [50.0–77.5]** | 60.0 [50.0–72.5]* | <0.0001 |
| HADS‐Anxiety | 3.8 ± 2. 8 | 3.3 ± 2.8 | 6.5 ± 3.2*,*** | 0.02 |
| HADS‐Depression | 2.0 [0.75–3.0] | 3.0 [1.0–6.5] | 6.5 [3.5–10.0]* , † | 0.01 |
Data from SF‐36, EQ‐5D, and HADS.
EQ‐5D, European quality of life–5 dimensions; HADS, hospital anxiety and depression scale; VAS, visual analogue scale.
*
P < 0.0167 comparison between HFpEF and non‐HF controls.
**
P < 0.0167 comparison between HFrEF and non‐HF controls.
***
P < 0.0167 comparison between HFpEF and HFrEF.
†
P < 0.05 comparison between HFpEF and HFrEF.