Table 1.
Rank and Haplotype frequency | ||||||||||
Our family study | The unrelated study reported[6] | |||||||||
HLA A-C-B-DRB1-DQB1 haplotype | (4n = 8608) | China | East China | |||||||
A∗ | C∗ | B∗ | DRB1∗ | DQB1∗ | Rank† | HF (%) | Rank | HF (%) | Rank | HF (%) |
30:01 | 06:02 | 13:02 | 07:01 | 02:02 | 1 | 4.98 | 1 | 3.70 | 1 | 4.50 |
02:07 | 01:02 | 46:01 | 09:01 | 03:03 | 2 | 3.18 | 2 | 2.46 | 3 | 2.56 |
33:03 | 03:02 | 58:01 | 03:01 | 02:01 | 3 | 2.83 | 3 | 2.40 | 2 | 2.89 |
33:03 | 03:02 | 58:01 | 13:02 | 06:09 | 4 | 1.45 | 5 | 1.06 | 4 | 1.43 |
11:01 | 08:01 | 15:02 | 12:02 | 03:01 | 5 | 1.30 | 4 | 1.13 | 5 | 1.01 |
02:07 | 01:02 | 46:01 | 08:03 | 06:01 | 6 | 0.94 | 6 | 0.93 | 7 | 0.92 |
33:03 | 14:03 | 44:03 | 13:02 | 06:04 | 6 | 0.94 | 7 | 0.74 | 6 | 0.95 |
11:01 | 04:01 | 15:01 | 04:06 | 03:02 | 8 | 0.86 | 12 | 0.56 | 8 | 0.60 |
02:01 | 03:04 | 13:01 | 12:02 | 03:01 | 9 | 0.60 | 10 | 0.58 | 9 | 0.58 |
02:01 | 03:03 | 15:11 | 09:01 | 03:03 | 9 | 0.60 | 22 | 0.36 | 18 | 0.40 |
11:01 | 03:04 | 13:01 | 15:01 | 06:01 | 11 | 0.58 | 9 | 0.64 | 11 | 0.56 |
01:01 | 06:02 | 57:01 | 07:01 | 03:03 | 12 | 0.53 | 14 | 0.45 | 16 | 0.46 |
24:02 | 01:02 | 54:01 | 04:05 | 04:01 | 13 | 0.51 | 16 | 0.44 | 14 | 0.47 |
11:01 | 07:02 | 40:01 | 08:03 | 06:01 | 14 | 0.48 | 17 | 0.42 | 13 | 0.49 |
24:02 | 14:02 | 51:01 | 09:01 | 03:03 | 14 | 0.48 | 26 | 0.31 | 19 | 0.35 |
11:01 | 01:02 | 46:01 | 09:01 | 03:03 | 16 | 0.46 | 11 | 0.58 | 10 | 0.56 |
11:01 | 07:02 | 40:01 | 09:01 | 03:03 | 17 | 0.45 | 21 | 0.36 | 15 | 0.46 |
33:03 | 07:06 | 44:03 | 07:01 | 02:02 | 18 | 0.43 | 13 | 0.47 | 17 | 0.45 |
01:01 | 06:02 | 37:01 | 10:01 | 05:01 | 19 | 0.39 | 8 | 0.66 | 12 | 0.56 |
11:01 | 14:02 | 51:01 | 09:01 | 03:03 | 19 | 0.39 | 25 | 0.31 | 20 | 0.34 |
24:02 | 03:04 | 13:01 | 12:02 | 03:01 | 19 | 0.39 | >20‡ | – | >20‡ | – |
The same ranks were assigned to different haplotypes if their HFs were equal.
>20 means that the ranks and frequencies of some haplotypes outside of the top 20 list of all the areas showed in study reported.[6]
HF: Haplotype frequency; –: No data.