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. 2021 Jul 24;13:205–217. doi: 10.2147/EB.S317186

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© 2021 Silverstein et al.

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Scatterplots of relationships between left eye (OS) perfusion and vessel density values as predictors of left eye macula central subfield (CSF) thickness and cube volume, for the entire sample. Each panel shows all data points along with the best-fitting least-squares regression line (in red, labeled as “estimate”), upper and lower 95% confidence limits for a single mean response (inner, blue lines), and prediction limits for new observations (outer, cyan lines). The Spearman rho correlation coefficient and accompanying p-value, expressing the strength of the relationship between variables, is shown in the lower right portion of each panel. Panels display relationships between: (A) perfusion density and CSF thickness; (B) vessel density and CSF thickness; (C) perfusion density and cube volume; and (D) vessel density and cube volume. The same overall pattern of positive relationships existed in the right eye data, but relationships between variables were weaker than for the left eye in all cases. The relationships between variables were similar for patients and control subjects when considered as separate groups.