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. 2021 Jul 24;14:3501–3521. doi: 10.2147/JIR.S312385

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© 2021 Zou et al.

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Exosomes secretion and IL-1β release in the lung of mice. (A) CD63 and AnX2 (exosome marker) release increased in the lung of mice receiving PPE instillation. (B) Bar graph shows enhanced staining of exosomes markers in the lung (n=6) (C) Representative images showed exosome release and (D) Bar graph shows increased exosome counts in lung lavages from mice receiving PPE instillation (n=5–6). (E) Representative photomicrographs depicts IL-1β-containing exosomes. (F) The PCC of CD63 (green) vs IL-1β (red) was significantly increased in the mice receiving PPE. *P<0.05 vs PBS treatment.