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Cold restraint stress-induced ulcers in rats. (a) Negative control treated with distilled water 10 ml/kg/day); (b) negative control treated with 100 mg/kg/day crude extract; (c) negative control treated with 200 mg/kg/day crude extract; (d) negative control treated with 400 mg/kg/day crude extract. (e) Positive control treated with the standard (cimetidine 100 mg/kg/day). All were pretreated with only a single dose.
