Fig. 3. Effect of rosiglitazone on the adipogenic differentiation of cADSCs. cADSCs were induced to adipogenic differentiation under MDI, MDRI, and MDRI + GW9662 conditions for 21 days. (A) Oil Red-O staining images. Scale bar indicates 50 µm. (B) Quantification of the stained lipid droplets. The results are presented as mean ± SEM.

cADSC, canine adipose-derived stem cell; MDI, 3-isobutyl-1-methylxanthine + dexamethasone + insulin; MDRI, and 3-isobutyl-1-methylxanthine + dexamethasone + rosiglitazone + insulin; SEM, standard error of mean.

^*p < 0.001 vs. MDI, ^†p < 0.001 vs. MDRI.