Fig. 5. Effect of rosiglitazone on the mRNA expression of gene expressions related to adipogenic differentiation of cADSCs. cADSCs were induced to adipogenic differentiation under MDI, MDRI, and MDRI + GW9662 for 14 days. Expression of (A) FABP4, (B) LPL, and (C) LEPTIN mRNAs was quantified by qRT-PCR. The results are presented as mean ± SEM.

cADSC, canine adipose-derived stem cell; MDI, 3-isobutyl-1-methylxanthine + dexamethasone + insulin; MDRI, and 3-isobutyl-1-methylxanthine + dexamethasone + rosiglitazone + insulin; FABP4, fatty acid-binding protein 4; LPL, lipoprotein lipase; qRT-PCR, quantitative real-time reverse-transcription polymerase chain reaction; SEM, standard error of mean.

^*p < 0.01, ^†p < 0.001 vs. MDI, ^‡p < 0.05, ^§p < 0.001 vs. MDRI.