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. 2021 Jul 17;70:103477. doi: 10.1016/j.ebiom.2021.103477

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© 2021 Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — Combined analysis of ISGs in PBMC and kidney of SLE and LN patients. (a) Violin plots showing TLR family expression in each cell type. (b) Thirty-one common ISGs expressed in PBMC and kidney were selected for further analysis. (c) Heatmap showing expression of 31 common ISGs in each cell type. The red arrow indicates which cell types are active regarding the 31 ISGs. (d) Heatmap showing expression of transcription factors related to ISG regulation in PBMCs from SLE patients. The red arrow indicates which cell types are active regarding these transcription factors. (e) Expression of transcription factors related to ISG regulation in kidneys of SLE patients. (f) Protein-Protein Interaction (PPI) network of transcription factors in PBMCs and kidneys of SLE patients (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.).