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The interobserver variation among VTAs. (a) Heatmap of the aTIL scores (as reference) and mTILs scores provided by three pathologists in both cohorts. (b) The CV was negatively correlated with TIL density, while there was no correlation between the CV and the TSR. (c) The distribution of CVs among the cases in both cohorts. (d) Differences in TIL density and TSR between the CV-low and CV-high cases in the SYSUCC cohort (CV cutoff at 0.3) and TCGA cohort (CV cutoff at 0.4).
