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. 2021 Mar 23;110(8):1299–1307. doi: 10.1007/s00392-021-01837-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Fixed-effects meta-analysis model of all trials, excluding AFFIRM-AHF, detailing the pooled effect of intravenous iron on the composite of first hospitalisations for heart failure or cardiovascular mortality (a), and first hospitalisation for heart failure (b) and cardiovascular mortality (c) alone. Although not included in the pooled analysis, odds ratios and 95% confidence intervals are presented for AFFIRM-AHF for comparison. IV intravenous, CI confidence interval