Table 2.
MPO and NT-pro-BNP levels and PC parameters over time and significance of means between response groups
| Rpts | NRpts | p R vs NR | |
|---|---|---|---|
| 0d | |||
| MPO (ng/ml) | 504 (316-769) | 134 (79-300) | <0.001 |
| WD (m) | 146 ± 200 | 293 ± 264 | 0.021 |
| EF (%) | 28.4 ± 6.1 | 26.1 ± 4.7 | 0.437 |
| NYHA III + IV (n[%]) | 30 [88%] | 12 [63%] | 0.043 |
| NTpBNP (ng/ml) | 2380 (854-6570) | 2008 (1151-3854) | 0.707 |
| 30d | |||
| MPO (ng/ml) | 216 (84-483) | 215 (101-528) | 0.626 |
| WD (m) | 308 ± 203 | 290 ± 260 | 0.776 |
| NYHA III + IV (n[%]) | 7 [20%] | 13 [68%] | 0.001 |
| 90d | |||
| MPO (ng/ml) | 188 (109-395) | 120 (66-364) | 0.328 |
| WD (m) | 350 ± 175 | 369 ± 248 | 0.816 |
| EF (%) | 34.1 ± 10.8 | 27.8 ± 8.6 | 0.028 |
| NYHA III + IV (n[%]) | 5 [15%] | 13 [68%] | <0.001 |
| NTpBNP (ng/ml) | 2257 (574-4531) | 1885 (1036-3696) | 0.933 |
Data are shown as Mean ± SD or median (interquartile range) for not normally distributed values
Rpts responders, NRpts non-responders, WD walking distance in 6-minute walk test, LVEF left-ventricular ejection fraction, 0d baseline, 30d 30 days after implantation, 90d 90 days after implantation
p < 0.05 was considered statistically significant