Fig. 3.

CXCR2 mediates peritoneal metastasis and binding to ECM proteins. CT-26 cells were injected intraperitoneally in laparotomized animals and mice received daily treatment with vehicle or the CXCR2 antagonist (10 mg/kg). After 10 days A the peritoneum was photographed and B the number of macroscopic tumor nodules was quantified in the peritoneum cavity. C Expression of CXCL2 mRNAs using qRT-PCR in tissue samples from the incisional line. Data represents mean ± SEM and n = 4. ^#P < 0.05 vs Sham and *P < 0.05 vs Vehicle