Table 8:

Clinical scenarios in which PTeye™ was found to be most helpful for endocrine surgeons (PG, parathyroid gland; FSA, frozen section analyses; PTH, parathyroid hormone)

Type of operative procedure	The clinical scenario in which PTeye™ was most beneficial
Thyroid procedures	Thyroid procedures where the surgeon saw only one PG with low confidence: In such scenarios, PTeye™ can help identify at least one PG before autotransplantation, if the gland is found to be devascularized by the surgeon. Finding incidentally removed PG(s): At the conclusion of each thyroid case, thyroid specimens can be scanned for accidentally excised PGs that can then be autotransplanted. Graves’ Disease: Due to a hypervascular thyroid, PG identification can be challenging and can be aided with PTeye™ Malignant thyroid disease: If the case involves lymph node dissection, PTeye™ can help identify at least one PG that could be autotransplanted, if found to be devascularized following extensive neck dissection. Hashimoto’s thyroiditis with associated reactive adenopathy: PTeye™ can help discern lymph nodes from PG. Large multinodular/substernal goiters: PTeye™ can help identify PG(s) despite the distortion of anatomy.
Parathyroid procedures	Non-localized cases: PTeye™ can be used to scan thyroid, thyrothymic ligament, carotid sheath as necessary Concurrent Hashimoto’s thyroiditis with associated lymphadenopathy: To discern lymph nodes from PG. Re-operative cases: PTeye™ can help identify and confirm PG in a scarred or distorted anatomical field. Localized and non-localized cases: PTeye™ can improve surgeon confidence at all levels of experience. PTeye™ may lead to a decrease in the use of FSA/tissue aspirate PTH analysis.