Figure 6:

Model 4. Model 4 builds upon model 3 by adding systolic blood pressure as a latent variable that directly influences both white matter hyperintensity burden and white matter fractional anisotropy. Years of education and sex were regressed from all latent variables modeled. Intracranial volume was regressed from white matter hyperintensity burden. Note: EF = executive function; CWI = color word interference; PS = processing speed; WMFA = white matter fractional anisotropy; FA = fractional anisotropy; IFOF = inferior frontal occipital fasciculus; SLF = superior longitudinal fasciculus; WMH = white matter hyperintensity burden; BP = blood pressure; SYS = systolic; EDU = years of education; ICV = intracranial volume.