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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Kidney Int. 2021 Apr 6;100(2):311–320. doi: 10.1016/j.kint.2021.03.025

Figure 8 |. 2-Bromodifluoroacetylamino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid o-tolylamide (TMinh-23) effect on vascular smooth muscle contractions in wild-type rat aorta.

Figure 8 |

(a) Representative traces showing isometric contractions in response to high K+ (60 mM) and U46619 in rat aorta treated with vehicle (top) or 3 μM TMinh-23 (bottom). (b) (Left) U46619 concentration-response curves in the absence or presence of 3 μM TMinh-23. (Right) Maximum U46619 response in the absence or presence of 3 μM TMinh-23. (c) High K+-induced peak contraction in the absence or presence of 3 μM TMinh-23. N = 6 experiments per group; Student’s t test was used. NS, not significant; PSS, physiological salt solution.