Table 1.
Participant Baseline Characteristics by Transplant Listing Status
| Not listed | Listed | P-value* | |
|---|---|---|---|
| (n=583) | (n=194) | ||
| Age at randomization, years | 0.000 | ||
| N | 583 | 194 | |
| Median (Q1, Q3) | 65 (57, 72) | 60 (54, 64) | |
| Female | 0.051 | ||
| 193/583 (33%) | 49/194 (25%) | ||
| Race | 0.002 | ||
| American Indian or Alaskan Native | 2/567 (0%) | 3/180 (2%) | |
| Asian | 164/567 (29%) | 27/180 (15%) | |
| Native Hawaiian or Other Pacific Islander | 3/567 (1%) | 3/180 (2%) | |
| Black or African American | 45/567 (8%) | 18/180 (10%) | |
| White | 352/567 (62%) | 129/180 (72%) | |
| Multiple Races Reported | 1/567 (0%) | 0/180 (0%) | |
| Degree of ischemia on stress test | 0.008 | ||
| Moderate | 340/575 (59%) | 136/194 (70%) | |
| Severe | 235/575 (41%) | 58/194 (30%) | |
| Hypertension | 0.520 | ||
| 537/581 (92%) | 174/192 (91%) | ||
| Diabetes | 0.658 | ||
| 330/583 (57%) | 114/194 (59%) | ||
| Smoking status | 0.030 | ||
| Never smoked | 280/583 (48%) | 91/194 (47%) | |
| Former smoker | 231/583 (40%) | 91/194 (47%) | |
| Current Smoker | 72/583 (12%) | 12/194 (6%) | |
| Previous myocardial infarction | 0.095 | ||
| 108/583 (19%) | 25/193 (13%) | ||
| Previous heart failure | 0.255 | ||
| 107/583 (18%) | 28/194 (14%) | ||
| Previous stroke | 0.467 | ||
| 54/583 (9%) | 14/194 (7%) | ||
| History of cerebrovascular disease or PAD† | 0.016 | ||
| 112/583 (19%) | 22/194 (11%) | ||
| Previous PCI‡ | 0.992 | ||
| 109/583 (19%) | 37/194 (19%) | ||
| Previous CABG§ | 0.119 | ||
| 17/583 (3%) | 11/194 (6%) | ||
| Ejection fraction (%) | 0.398 | ||
| N | 463 | 156 | |
| Median (Q1, Q3) | 58 (50, 64) | 59 (51, 64) | |
| On dialysis | 0.000 | ||
| 254/583 (44%) | 161/194 (83%) | ||
| Duration of dialysis (years) | 0.004 | ||
| N | 224 | 145 | |
| Median (Q1, Q3) | 3 (1, 6) | 2 (1, 4) | |
| Dialysis type | 0.039 | ||
| Peritoneal dialysis | 29/247 (12%) | 31/157 (20%) | |
| eGFR among those not receiving dialysis (ml/min/1.73m2) | 0.000 | ||
| N | 329 | 33 | |
| Median (Q1, Q3) | 23 (18, 27) | 16 (14, 20) | |
| SAQ# Summary score | 0.000 | ||
| N | 536 | 188 | |
| Median (Q1, Q3) | 74 (58, 88) | 92 (77, 100) | |
| SAQ# Angina Frequency score | 0.000 | ||
| N | 536 | 188 | |
| Median (Q1, Q3) | 90 (80, 100) | 100 (90, 100) | |
| SAQ# Physical Limitation score | 0.000 | ||
| N | 416 | 159 | |
| Median (Q1, Q3) | 75 (50, 100) | 92 (71, 100) | |
| SAQ# Quality of Life score | 0.000 | ||
| N | 535 | 188 | |
| Median (Q1, Q3) | 63 (38, 88) | 88 (63, 100) | |
| Canadian Cardiovascular Society angina class | 0.000 | ||
| None | 171/583 (29%) | 121/193 (63%) | |
| I | 118/583 (20%) | 37/193 (19%) | |
| II | 264/583 (45%) | 34/193 (18%) | |
| III | 30/583 (5%) | 1/193 (1%) | |
| New York Heart Association class | 0.009 | ||
| I | 99/337 (29%) | 37/78 (47%) | |
| II | 237/337 (70%) | 41/78 (53%) | |
| III | 1/337 (0%) | 0/78 (0%) | |
| Type of stress testing | 0.002 | ||
| Nuclear | 358/581 (62%) | 121/194 (62%) | |
| ECHO | 100/581 (17%) | 52/194 (27%) | |
| CMR†† | 1/581 (0%) | 0/194 (0%) | |
| ETT‡‡ | 122/581 (21%) | 21/194 (11%) | |
| Treatment strategy | 0.694 | ||
| Initial Invasive | 294/583 (50%) | 94/194 (48%) |
When the denominator is smaller than the column title population size, it represents the non-missing statistics
*
P-values were obtained using the Wilcoxon Rank Sum test for continuous variables. For categorical variables, Pearson’s chi-squared test was used
†
PAD: peripheral arterial disease
‡
PCI: percutaneous coronary intervention
§
CABG: coronary artery bypass graft
ǁ
eGFR: estimated glomerular filtration rate
#
SAQ: Seattle Angina Questionnaire
**
ECHO: echocardiography
††
CMR: Cardiac Magnetic Resonance Imaging
‡‡
ETT: exercise treadmill test