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. 2021 Mar 1;15(8):2322–2335. doi: 10.1038/s41396-021-00926-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Plasmid host genera distribution by compartment. b Distribution of plasmid sequence lengths with predicted mobilities. c Graph representing the association between replicon alleles. F-type nodes are coloured pink. Line weight is proportional to frequency of association in the sample. d Plasmid GC-content subtracted from host chromosome GC-content. A value greater than zero indicates the plasmid is AT-richer than the host. Only plasmids with circularised host chromosomes were used (565/726).