Table 2.
Geometric Mean Concentrations* (nmol/mL) of Carotenoids and Retinol by Extent of Prostate Biopsy Cores Inflamed in 235 Men without Prostate Cancer and Irrespective of Indication for Biopsy**, Placebo Arm, PCPT
None | 95%CI | Any | 95%CI | Some | 95%CI | All | 95%CI | p-trend | |
---|---|---|---|---|---|---|---|---|---|
β-cryptoxanthin | 0.15 | (0.13,0.097) | 0.16 | (0.14,0.17) | 0.16 | (0.15,0.18) | 0.15 | (0.132,0.17) | 0.91 |
Lycopene | 0.63 | (0.56,0.17) | 0.64 | (0.61,0.69) | 0.64 | (0.59,0.69) | 0.66 | (0.59,0.74) | 0.54 |
α-carotene | 0.088 | (0.074,0.11) | 0.085 | (0.077,0.093) | 0.088 | (0.079,0.098) | 0.078 | (0.066,0.092) | 0.46 |
β-carotene | 0.46 | (0.38,0.55) | 0.43 | (0.39,0.47) | 0.44 | (0.39,0.50) | 0.41 | (0.34,0.48) | 0.35 |
Sum of these carotenoids | 1.42 | (1.26,1.59) | 1.41 | (1.31,1.50) | 1.41 | (1.31,1.53) | 1.38 | (1.24,1.55) | 0.78 |
Retinol | 2.42 | (2.27,2.58) | 2.34 | (2.27,2.43) | 2.36 | (2.26,2.45) | 2.32 | (2.19,2.46) | 0.18 |
Adjusted for baseline age, race, family history of prostate cancer, serum cholesterol; linear models for P-trend across none, some, all cores inflamed adjusted for baseline age, race, family history of prostate cancer, serum cholesterol, tested at α=0.05 with no cores inflamed as the reference.
92.8% did not have a clinical indication for biopsy