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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Nutr Cancer. 2021 Jan 29;74(1):141–148. doi: 10.1080/01635581.2021.1879879

Table 3.

Association* of Carotenoids and Retinol with Extent of Prostate Biopsy Cores Inflamed in 235 Men without Prostate Cancer and Irrespective of Indication for Biopsy**, Placebo Arm, PCPT

Extent of Biopsy Cores Inflamed
None Any Some All
Tertile*** N N OR (95%CI) N OR (95%CI) N OR (95%CI)
β-cryptoxanthin 1 25 53 1.00 33 1.00 20 1.00
2 12 67 2.67 (1.19,5.99) 46 2.98 (1.27,6.97) 21 2.16 (0.83,5.63)
3 16 62 1.80 (0.84,3.82) 43 2.03 (0.91,4.53) 19 1.40 (0.55,3.53)
Lycopene 1 16 62 1.00 42 1.00 20 1.00
2 22 57 0.56 (0.26,1.21) 38 0.57 (0.26,1.28) 19 0.54 (0.21,1.38)
3 15 63 1.38 (0.59,3.25) 42 1.33 (0.55,3.23) 21 1.51(0.56,4.08)
α-carotene 1 19 59 1.00 37 1.00 22 1.00
2 16 63 1.30 (0.60,2.79) 43 1.39 (0.63,3.12) 20 1.13 (0.45,2.83)
3 18 60 1.02 (0.49,2.22) 42 1.16 (0.52,2.58) 18 0.82 (0.33,2.07)
β-carotene 1 16 62 1.00 41 1.00 21 1.00
2 19 60 0.73 (0.33,1.58) 41 0.76 (0.34,1.72) 19 0.65 (0.26,1.66)
3 18 60 0.81 (0.37,1.79) 40 0.83 (0.36,1.89) 20 0.79 (0.31,2.03)
Sum of these carotenoids 1 22 56 1.00 38 1.00 18 1.00
2 13 66 1.35 (0.63,2.90) 43 1.34 (0.60,2.99) 23 1.38 (0.55,2.99)
3 18 60 1.33 (0.61,2.90) 41 1.32 (0.58,3.00) 19 1.35 (0.53,3.49)
Retinol 1 17 61 1.00 42 1.00 19 1.00
2 15 64 1.31 (0.59,2.89) 41 1.21 (0.53,2.78) 23 1.53 (0.60,3.92)
3 21 57 0.78 (0.35,1.65) 39 0.75 (0.33,1.70) 18 0.77 (0.30,1.99)
*

Models adjusted for baseline age, cholesterol, race, family history prostate cancer.

**

92.8% did not have a clinical indication for biopsy

***

Tertile ranges (nmol/mL): β-cryptoxanthin: T1: 0.0139 to <0.122, T2: 0.122 to <0.203, T3: 0.203 to 0.728; lycopene: T1: 0.0700 to <0.548, T2:0.548–0.782, T3:0.786 to 1.90; α-carotene: T1:0.0169 to <0.0655, T2: 0.0655 to <0.111, T3: 0.111 to 0.894; β-carotene: T1: 0.0437 to <0.326, T2: 0.326 to <0.567, T3: 0.567 to 6.63; sum of these carotenoids: T1: 0.145 to <1.18, T2: 1.18 to <1.67, T3: 1.67–9.31; retinol: T1: 1.36 to <2.15, T2: 2.15 to <2.609, T3: 2.609 to 5.15.