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. 2021 Feb 21;15(8):2233–2247. doi: 10.1038/s41396-021-00919-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A A stacked barplot showing the number of replicates exhibiting growth for each EPD and the ancestral cocultures across a dilution series. B Growth rate and carrying capacity of pairings of ancestral and evolved clonal isolates of Dv and Mm from EPD-03 and EPD-09. C Excess-Over-Bliss analysis for estimating synergistic and antagonistic interactions of Dv/Mm clonal isolate pairings. D Growth rate and yield for three evolved Dv/Mm pairings from each EPD.