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. 2021 Jul 28;11:15336. doi: 10.1038/s41598-021-94789-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Pairwise genomic variation among Clone 1 M. massiliense isolates. Pairwise SNP distances were calculated for all Clone 1 isolates in the study (n = 58). (A) Isolate pairs are categorized as between-patient or within-patient. Between patient isolates in the same cluster (Cluster 1 or Cluster 2) are further categorized as belonging to known outbreaks (red) or as sporadic, unrelated isolates (blue). (B) The relationship between accessory gene content for Clone 1 isolate pairs, measured as % accessory genes for each isolate pair (# accessory genes/# of genes in pan genome) and core genome similarity (shown as pairwise SNP distance) is shown as a scatter plot.