Table 3.
Determinants of presentation in advanced stage (stage III-IV) at diagnosis.
| Characteristics | Patients |
Patients with |
Crude odds ratio |
Adjusted∗ odds ratio |
|||||
|---|---|---|---|---|---|---|---|---|---|
| assessed |
advanced |
(95% CI) | (95% CI) | ||||||
| stage (III-IV) | |||||||||
| n | n (%) | ||||||||
| Patients with staging information | 1973 | 903 | (45.8) | ||||||
| Centre | |||||||||
| CM-VI, Casablanca | 829 | 360 | (43.4) | 1.00 | 1.00 | ||||
| INO, Rabat |
1144 |
543 |
(47.5) |
1.18 |
(0.98 - |
1.40) |
1.20 |
(0.99 - |
1.43) |
| Period of diagnosis | |||||||||
| 2008–2012 | 846 | 403 | (47.6) | 1.00 | 1.00 | ||||
| 2013–2017 |
1127 |
500 |
(44.4) |
0.88 |
(0.72 - |
1.04) |
0.95 |
(0.75 - |
1.17) |
| Age at diagnosis (years) | |||||||||
| <30 | 40 | 18 | (45.0) | 1.05 | (0.47 - | 1.88) | 1.05 | (0.50 - | 1.95) |
| 30-39 | 305 | 133 | (43.6) | 1.00 | 1.00 | ||||
| 40-49 | 679 | 309 | (45.5) | 1.08 | (0.80 - | 1.39) | 1.05 | (0.78 - | 1.39) |
| 50-59 | 569 | 266 | (46.7) | 1.14 | (0.82 - | 1.46) | 1.07 | (0.73 - | 1.46) |
| 60-69 | 269 | 130 | (48.3) | 1.21 | (0.84 - | 1.64) | 1.10 | (0.70 - | 1.60) |
| 70+ |
108 |
47 |
(43.5) |
0.99 |
(0.61 - |
1.49) |
0.84 |
(0.44 - |
1.32) |
| Residence | |||||||||
| Urban | 1572 | 712 | (45.3) | 1.00 | 1.00 | ||||
| Semi-urban | 170 | 77 | (45.3) | 1.00 | (0.70 - | 1.34) | 1.01 | (0.71 - | 1.37) |
| Rural |
231 |
114 |
(49.4) |
1.18 |
(0.88 - |
1.53) |
1.20 |
(0.89 - |
1.56) |
| Health insurance coverage | |||||||||
| None | 550 | 257 | (46.7) | 1.00 | 1.00 | ||||
| Covered | 1195 | 528 | (44.2) | 0.91 | (0.73 - | 1.09) | 0.93 | (0.72 - | 1.19) |
| RAMed | 925 | 418 | (45.2) | 0.94 | (0.76 - | 1.15) | 1.01 | (0.76 - | 1.29) |
| Employee's insurance |
270 |
110 |
(40.7) |
0.78 |
(0.57 - |
1.03) |
0.77 |
(0.54 - |
1.03) |
| Marital status | |||||||||
| Never married | 286 | 118 | (41.3) | 1.00 | 1.00 | ||||
| Ever married |
1571 |
726 |
(46.2) |
1.22 |
(0.95 - |
1.57) |
1.10 |
(0.74 - |
1.47) |
| Parity | |||||||||
| None | 411 | 176 | (42.8) | 1.00 | 1.00 | ||||
| 1-2 | 472 | 219 | (46.4) | 1.16 | (0.87 - | 1.48) | 1.13 | (0.79 - | 1.52) |
| 3-4 | 491 | 228 | (46.4) | 1.15 | (0.88 - | 1.49) | 1.15 | (0.82 - | 1.56) |
| 5+ |
399 |
195 |
(48.9) |
1.28 |
(0.96 - |
1.66) |
1.22 |
(0.84 - |
1.68) |
| Menopause status | |||||||||
| No | 975 | 436 | (44.7) | 1.00 | 1.00 | ||||
| Yes |
836 |
393 |
(47.0) |
1.10 |
(0.91 - |
1.31) |
0.99 |
(0.76 - |
1.27) |
| Family history of breast cancer | |||||||||
| No | 1600 | 1490 | (93.1) | 1.00 | 1.00 | ||||
| Yes |
228 |
221 |
(96.9) |
0.93 |
(0.69 - |
1.22) |
0.91 |
(0.65 - |
1.19) |
| Interval between symptoms onset and first consultation (months) | 1.03 | (1.02 - | 1.04) | 1.03 | (1.02 - | 1.04) | |||
CM-VI: Centre Mohammed VI pour le traitement des cancers; INO: Institut National d’Oncologie; RAMed: Régime d’Assistance Médicale; CI: Confidence Interval; ∗ Adjusted for all the variables listed in the table.