Table 1.
Baseline characteristics of the cohort.
| Feature | Overall (N = 209) |
|---|---|
| Age, years | 59 [44, 74] |
| Female sex | 92 (44) |
| Charlson comorbidity index (CCI) | 2 [0, 4] |
| High comorbidity (CCI ≥ 5) | 42 (20.1) |
| Comorbidities | |
| Arterial hypertension | 100 (47.8) |
| Cardiovascular disease | 35 (16.7) |
| Diabetes | 50 (23.9) |
| NEWS2 on admission | 4 [3, 6] |
| Disease severity | |
| Mild | 22 (10.5) |
| Moderate | 87 (41.6) |
| Severe | 100 (47.8) |
| Time from symptom onset to hospital admission, days | 7 [5, 10] |
| Gastrointestinal symptoms | |
| Diarrhea | 40 (19.1) |
| Vomiting | 20 (9.6) |
| Abdominal pain | 16 (7.7) |
| Need for ICU admission during hospitalization | 81 (38.8) |
| Laboratory tests on admission | |
| AST (U/L) | 35 [24, 56] |
| ALT (U/L) | 28 [18, 54] |
| Alkaline phosphatase (U/L) | 66 [50, 84] |
| Gamma-glutamyl transferase (U/L) | 54 [33, 121] |
| Total billirubin (mg/dL) | 0.5 [0.4, 0.6] |
| Albumin (g/L) | |
| Lymphocyte count (×109/L) | 1.038 [0.67, 1.501] |
| Platelets (×109/L) | 224 [179, 275] |
| D-dimer (μg/ml) | 880 [420, 1850] |
| Lactate dehydrogenase (U/L) | 298 [219, 448] |
| Prescribed medications | |
| Low-molecular-weight heparin | |
| Prophylactic dose | 74 (35.4) |
| Intermediary dose | 43 (20.6) |
| Therapeutic dose | 36 (17.2) |
| Glucocorticoids | 136 (65.1) |
| Antibiotics | 131 (62.7) |
Continuous data are presented as median [1st, 3rd quartile]. Categorical variables are presented as counts (percentages).