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. 2021 Jul 28;9(15):e14982. doi: 10.14814/phy2.14982

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© 2021 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Relationship between relative changes in MAP from baseline (Δ%MAP) and concomitant relative changes in CBF (Δ%CBF) when MAP decreases and increases including (left panel) and excluding (right panel) the utilization of cardiovascular drugs to manipulate MAP. These data represent an updated analysis initially published by Numan et al. (2014) Note the consistent pressure‐passive nature of CBF in the pharmacological data (left panel) and the small plateau present in the non‐pharmacological data (right panel)