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SCA7 mice have an accumulation of ATXN7 protein in the nuclei of cells surrounding putative phrenic and hypoglossal motor neurons. (A-D) Representative images of ChAT- (green), ATXN7- (red) and DAPI- (blue) stained cervical spinal cord and medulla of 10-week-old wild-type (WT) and SCA7 mice. Putative phrenic motor nucleus of wild-type (A) and (B) SCA7 mice. Hypoglossal motor nucleus of wild-type (C) and SCA7 (D) mice. ATXN7 aggregates are indicated with triangles. Scale bars: 40 µm.
