Fig. 6.

SCA7 mice have reduced weights and increased motor and behavioral disorder at 8 and 9 weeks of age. (A) Weights of wild-type (WT) and SCA7 mice at indicated ages. (B-D) Scores for gait (B), kyphosis (C) and ledge tests (D) at indicated ages. Data are mean±s.e.m. Statistical significance was determined using a mixed-model two-way ANOVA, followed by a Bonferroni's post-hoc analysis (*P<0.05; **P<0.01; ***P<0.001; 4 and 8 weeks, n=10 wild type, n=11 SCA7; 9 weeks, n=10 wild type, n=7 SCA7).