TABLE 2.

Differentially expressed exosomal miRNAs among HSs and ARDS patients in the discovery cohort.

MicroRNAs	Fold change	Adjusted p-values
Upregulated miRNAs in ARDS
hsa-miR-142-5p	8.05	5.87E-06
hsa-miR-122-5p	19.00	1.03E-04
hsa-miR-223-3p	3.94	5.06E-04
hsa-Let-7d-3p	3.17	2.32E-03
hsa-miR-24-3p	4.77	2.32E-03
hsa-miR-130a-3p	5.67	4.13E-03
hsa-miR-98-3p	20.64	9.10E-03
hsa-miR-221-3p	9.78	0.013
hsa-miR-193a-5p	22.71	0.020
hsa-miR-1273a	15.34	0.022
Downregulated miRNAs in ARDS
hsa-Let-7a-5p	−1.64	0.011
hsa-miR-486-5p	−3.29	0.022

RNA-seq analysis of exosomal miRNAs from the plasma of ARDS patients (n = 8) compared with HSs (n = 10).