Table 2.
Group | Day2 | Day4 | Day6 | Day8 | Day10 | Day12 | Day14 | Day16 |
---|---|---|---|---|---|---|---|---|
SO | 294.33 ± 3.17 | 269.3 ± 3.21 | 237.0 ± 1.89 | 195.33 ± 2.23 | 146.33 ± 2.62 | 111.00 ± 3.32 | 74.50 ± 4.28 | 33.33 ± 6.09 |
(6.26%) | (14.23%) | (24.52%) | (37.79%) | (53.40%) | (64.65%) | (76.27%) | (89.38%) | |
NF | 274.0 ± 2.32aA | 245.3 ± 1.56aB | 192.2 ± 1.30aB | 145.50 ± 2.09aC | 103.3 ± 5.36aC | 68.83 ± 7.3aC | 37.83 ± 4.31aC | 5.50 ± 3.50aB |
(12.74%) | (21.87%) | (38.80%) | (53.66%) | (67.09%) | (78.08%) | (87.95%) | (98.25%) | |
CF5 | 275.2 ± 5.22aA | 240.8 ± 4.71aC | 198.3 ± 2.7aC | 150.83 ± 1.64aC | 113.7 ± 2.84aB | 70.33 ± 2.82aC | 41.67 ± 1.78aC | 9.33 ± 4.30aA |
(12.37%) | (23.30%) | (36.84%) | (51.96%) | (63.80%) | (77.60%) | (86.73%) | (97.03%) | |
CF10 | 273.2 ± 4.27aB | 239.8 ± 3.25aC | 187.3 ± 5.73aC | 142.50 ± 8.15aC | 99.33 ± 6.54aC | 65.00 ± 3.72aC | 38.00 ± 1.10aC | 4.33 ± 4.33aB |
(13.00%) | (23.62%) | (40.34%) | (54.62%) | (68.36%) | (79.30%) | {87.90%) | (98.62%) | |
EF5 | 283.33 ± 3.57 | 237.8 ± 5.71aC | 192.0 ± 7.01aC | 135.00 ± 8.08aC | 92.50 ± 9.68aC | 64.83 ± 5.91aC | 37.50 ± 4.74aC | 10.5 ± 6.67aA |
(9.77%) | (24.26%) | (38.85%) | (57.01%) | (70.54%) | (79.35%) | (88.06%) | (96.65%) | |
EF10 | 283.00 ± 4.20 | 238.0 ± 2.76aC | 182.3 ± 4.15aC | 131.83 ± 6.05aC | 91.00 ± 4.29aC | 59.50 ± 2.68aC | 34.83 ± 1.99aC | 4.33 ± 4.33aB |
(9.87%) | (24.21%) | (41.93%) | (58.01%) | (71.02%) | (81.05%) | (88.91%) | (98.62%) | |
AF5 | 277.0 ± 3.1 aA |
237.3 ± 5. 4aC |
186.7 ± 5.49aC | 129.00 ± 5.90aC | 90.67 ± 4.90aC | 59.00 ± 4.44aC | 38.00 ± 1.51aC | 2.67 ± 2.66aB |
(11.78%) | (24.42%) | (40.55%) | (58.92%) | (71.13%) | (81.21%) | (87.90%) | (99.15%) | |
AF10 | 270.3 ± 3.95aB | 241.0 ± 3.5aC | 188.0 ± 7.67aC | 128.67 ± 7.96aC | 89.33 ± 4.86aC | 57.17 ± 5.86aC | 35.17 ± 1.42aC | .00 ± .00aB |
(13.91%) | (23.25%) | (40.13%) | (59.02%) | (71.55%) | (81.79%) | (88.80%) | (100%) |
n = 6, Values are expressed as mean ± SEM, one way ANOVA,AP <0 0.05, BP < 0.01, Cp < 0.001,aagainst the negative control, Abbreviations: SO = Simple Ointment, NF = Nitrofurazone ointment, CF5 = 5% chloroform fraction, CF10 = 10% chloroform fraction, EF5 = 5% ethyl acetate fraction, EF10 = 10% ethyl acetate fraction, AF5 = 5% aqueous fraction, AF10 = 10% aqueous fraction. Initial wound size was 314 mm2.