| Coronavirus disease 2019 is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2. The spike protein of SARS-CoV-2 interacts with the angiotensin-converting enzyme 2 receptor present on the host cell surface, leading to viral entry and infection. |
| A 13-amino acid novel peptide inhibitor (FLDKFNHNFKDLF) has been designed to block the receptor-binding domain of the SARS-CoV-2 spike protein, which impedes its interaction with the host angiotensin-converting enzyme 2 receptor. |
| The 13-amino acid peptide inhibitor is expected to restrict virus interaction and fusion with the host cells, thereby making it a promising therapeutic candidate to combat coronavirus disease 2019. |
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