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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Gynecol Oncol. 2021 Jun 2;162(2):268–276. doi: 10.1016/j.ygyno.2021.05.020

Table 5.

Suggested criteria for the consideration of secondary cytoreductive surgery over medical management for recurrent endometrial cancer based on clinicopathologic and initial surgical features

Higher Consideration Lower Consideration
Features from time of diagnosis Age ≤ 70 at initial diagnosis
PFS1 ≥ 19 months
Endometrioid/Clear cell
FIGO Grade 1/2
Early stage I/II disease at diagnosis
BMI
Features from primary surgery No residual disease
Hospital stay ranging from 0–6 days
Received adjuvant radiation therapy
Received adjuvant chemotherapy
Features at time of recurrence Single site of disease Size of tumor
Distant site of recurrence

PFS1, time interval from initial surgery to first progression/recurrence; BMI, body mass index; FIGO, International Federation of Gynecology and Obstetrics