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. 2021 Jul 28;11(7):e045797. doi: 10.1136/bmjopen-2020-045797

Table 4.

HRs for type 2 diabetes in men with prostate cancer on GnRH agonists for different periods of exposure

Years of exposure Number of events Number of patients HR 95% CI aHR* 95% CI
ADT-free cohort 570 14 502 ref. Ref.
0–1 369 6800 1.41 1.23 to 1.61 1.38 1.21 to 1.58
1–2 139 2177 1.60 1.33 to 1.93 1.59 1.32 to 1.92
2–3 105 1330 1.77 1.44 to 2.18 1.76 1.42 to 2.17
3–5 96 1151 1.74 1.40 to 2.16 1.73 1.42 to 2.17
>5 50 606 1.58 1.18 to 2.11 1.57 1.17 to 2.10

*Adjusted for age and stage.

ADT, androgen deprivation therapy; GnRH, gonadotropin-releasing hormone.