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. 2021 Jul 15;9:662133. doi: 10.3389/fcell.2021.662133

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Copyright © 2021 Joanne, Hovhannisyan, Bencze, Daher, Parlakian, Toutirais, Gao-Li, Lilienbaum, Li, Kordeli, Ferry and Agbulut.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Size distribution of plantaris muscle fibers is modified in DesKO mice after OVL. Size distribution of plantaris muscle fibers expressing only MHC-2a (A,B) or MHC-2b (D,E) for both genotypes (Ctr and DesKO) in basal condition (black line) or after 1 month of OVL (black dotted line). The gain or loss in these parameters was calculated compared to the corresponding basal condition for the Ctr + OVL and DesKO + OVL groups (C,F). Data are given as means ± SEM. For the size distribution, n = 4 for all conditions (n = 3 for Ctr + Basal group). DesKO, Desmin knock-out mice; Ctr, Control mice; OVL, mechanical overloading; MHC, myosin heavy chain. ns, non-significant, *p < 0.05.