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. 2021 Jul 15;11:626663. doi: 10.3389/fonc.2021.626663

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Copyright © 2021 Zhan, Gao, Wang, Li, Shen, Lu, Xu, Li and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Verification of SNHG3-miR-213-3p-ASF1B regulatory axis. (A) Left: the regulatory relationship between ASF1B and miR-214-3p was validated in luciferase reporter assay; right: the mRNA level of ASF1B in HepG2 cells was markedly downregulated by miR-214-3p overexpression. (B) Left: the regulatory relationship between lncRNA SNHG3 and miR-214-3p was validated in luciferase reporter assay; right: the mRNA level of miR-214-3p in HepG2 cells was significantly decreased by SNHG3 overexpression. **p < 0.01.